Here is a little map of France and its main cities, with the driving times and distances :

Driving times and distances:

Paris-Calais: 2.5 hours  290 kms
Paris-Lyon: 5.5 hours   460 kms
Paris-Brussels: 3 hours   280 kms
Paris-Dijon: 3 hours   300 kms
Paris-Strasbourg: 6 hours   500 kms
Paris-Quimper/Brest: 6 hours   550 kms
Paris-Bordeaux: 6-7 hours   600 kms
Paris-Rennes: 4 hours   430 kms
Paris-Marseille: 9-10 hours   775 kms
Lyon- Marseille/Montpellier: 3 hours   300 kms
Bordeaux-Toulouse: 2 hours   250 kms
Bordeaux-Biarritz/Bayonne: 1.5 hours   180 kms
Strasbourg-Mulhouse/Basel: 1.5 hours   150 kms
Strasbourg-Lyon: 6 hours    550 kms

1- Driving on the right.
2- Speed limits.
3- Driving licence.
4- Filling up the tank.
5- Highways.
6- Drinking and driving.
7- Driving times and distances.
8- Busy time on the roads.

Enjoy your driving!